TABLE 1.
Genotype of mice | Day of onset (mean ± sem) | Maximum score until d 27 (mean ± sem) | Time to peak (d; mean ± sem) | Accumulative score until d 27 (mean ± sem) |
---|---|---|---|---|
WT | 13.1 ± 0.6 | 3.3 ± 0.1 | 16.9 ± 0.8 | 31.7 ± 2.6 |
Ifnar1−/− | 14.1 ± 0.6 | 3.3 ± 0.1 | 16.6 ± 0.6 | 35.8 ± 2.4 |
IFNAR1Texcl | 16.6 ± 0.8*,† | 3.5 ± 0.2 | 20.8 ± 1.2‡,§ | 25.3 ± 4.7† |
P < 0.01, ‡P < 0.05, comparisons between IFNAR1Texcl mice versus WT mice. †P < 0.05, §P < 0.01, comparisons between IFNAR1Texcl mice versus Ifnar1−/− mice. n = 9 Mice/genotype.