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. 2015 Jul 31;99(1):175–188. doi: 10.1189/jlb.3A1214-598R

TABLE 2.

Clinical severity of WT and IFNAR1Texcl mice upon PBS or IFN-β administration

Genotype of mice Treatment Maximum score (mean ± sem) Accumulative score (mean ± sem)
IFNAR1Texcl PBS 3.7 ± 0.2 27.8 ± 2.5
IFNAR1Texcl rIFN-β 0.9 ± 0.1*,† 4.4 ± 3.1†,‡
WT rIFN-β 2.5 ± 0.5 24.8 ± 5.5
*

P < 0.05, ‡P < 0.01 compared with PBS-treated IFNAR1Texcl mice. †P <0.001 compared with IFN-β-treated WT mice. n = 5 Mice/genotype.