Table 2. Laboratory and immunologic manifestations.
| Parameters | Germinal center (+) (N = 28) |
Germinal center (-) (N = 65) |
P value |
|---|---|---|---|
| WBC (/µL) | 5,400 ± 1,872 | 5,341 ± 1,986 | 0.769 |
| Lymphocyte (/µL) | 1671 ± 576.6 | 1746 ± 689.4 | 0.788 |
| Hgb (g/dL) | 11.96 ± 1.669 | 12.46 ± 1.420 | 0.254 |
| Platelet (103/µL) | 208.6 ± 64.00 | 241.4 ± 70.98 | 0.111 |
| ESR (mm/hr) | 43.07 ± 26.91 | 40.51 ± 29.66 | 0.513 |
| CRP (mg/dL) | 0.62 ± 0.97 | 0.35 ± 0.52 | 0.046 |
| Ig G (mg/dL) | 2,053 ± 604.2 | 2,080 ± 737.1 | 0.691 |
| Ig A (mg/dL) | 335.1 ± 113.3 | 304.7 ± 128.9 | 0.072 |
| Ig M (mg/dL) | 139.2 ± 57.52 | 167.5 ± 161.6 | 0.904 |
| C3 (mg/dL) | 97.02 ± 23.68 | 100.6 ± 23.79 | 0.577 |
| C4 (mg/dL) | 19.88 ± 8.065 | 20.30 ± 9.235 | 0.997 |
| CH50 (U/mL) | 52.01 ± 15.76 | 51.74 ± 12.57 | 0.975 |
| RF (IU/mL) | 70.55 ± 94.61 | 35.84 ± 66.62 | 0.002 |
| Anti-SS-A/Ro (U/mL) | 171.8 ± 71.46 | 141.6 ± 85.47 | 0.020 |
| Anti-SS-B/La (U/mL) | 42.90 ± 62.63 | 46.26 ± 71.42 | 0.740 |
| RF (%) | 18/27 (66.7) | 26/63 (41.3) | 0.027 |
| Anti-SS-A/Ro (%) | 26/28 (92.9) | 55/65 (84.6) | 0.336 |
| Anti-SS-B/La (%) | 12/28 (42.9) | 25/65 (38.5) | 0.691 |
| Anti-dsDNA (%) | 7/26 (26.9) | 15/60 (24.6) | 0.819 |
Data are presented as means ± SD.
WBC, white blood cell; CRP, C-reactive protein; ESR, erythrocyte sedimentation rate; Hgb, hemoglobin; Ig, immunoglobulin; RF, rheumatoid factor.