Table 2. Univariate and multivariate analysis of risk factors of mortality.
Risk factors for mortality | Univariate analysis | Multivariate analysis | ||
---|---|---|---|---|
P value | Odds ratio (95% CI) | P value | Odds ratio (95% CI) | |
TE | < 0.001 | 8.42 (4.15-17.08) | < 0.001 | 7.110 (3.052-16.562) |
IRF | 0.001 | 3.41 (1.66-7.02) | 0.029 | 2.953 (1.116-7.818) |
PNH-cytopenia | 0.023 | 2.17 ( 1.11-4.21) | 0.020 | 2.547 (1.159- 5.597) |
LDH ≥ 1.5 × ULN | 0.009 | 4.99 (1.15-21.70) | 0.159 | 3.204 (0.633-16.230) |
Abdominal pain | 0.026 | 2.10 (1.08-4.08) | 0.162 | 1.828 (0.785-4.256) |
Dyspnea/Chest pain | 0.026 | 2.09 (1.086-4.024) | 0.855 | 1.077 (0.487-2.381) |
Hemoglobinuria | 0.636 | 0.86 (0.45-1.63) | 0.073 | 0.449 (0.187-1.077) |
Clone size | 0.391 | 1.01 (0.99-1.02) | 0.744 | 0.995 (0.967-1.024) |
CI, confidence interval; IRF, impaired renal function; LDH, lactate dehydrogenase; TE, thromboembolism; ULN, upper limit of normal.