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. 2016 Jan 26;31(2):310–314. doi: 10.3346/jkms.2016.31.2.310

Table 2. CYP2D6 genotypes and expected phenotypes.

CYP2D6 genotype Expected phenotype No. of EM alleles No. of PM alleles Frequency %
*1/*1 EM/EM 2 0 3 7.1
*1/*2 6 14.3
*2/*2 2 4.8
*1/*10 EM/IM 1 0 14 33.3
*1/*49 1 2.4
*1/*52 1 2.4
*2/*10 5 12.0
*1/*5 EM/PM 1 1 1 2.4
EM subtotal: 33 (78.6%)
*10/*10 IM/IM 0 0 4 9.5
*10/*41 1 2.4
*10/*49 1 2.4
*5/*10 IM/PM 0 1 3 7.1
IM subtotal: 9 (21.4%)
Total 42 100.0

EM, extensive metabolizer; PM, poor metabolizer; IM, intermediate metabolizer.