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Mean ± SEM ethanol intake (g/kg/2hr) and ethanol preference (%/2hr) in mice given continuous EtOH access (a, intake; b, preference; white bars, n=12), intermittent EtOH access (c, intake; d, preference; grey bars, n=10), and intermittent EtOH access after 10 days of social defeat stress (e, intake; f, preference; black bars, n=10) affected by intra-VTA microinjections of CRF-R1 antagonist CP376395 (0–0.6µg). *p<0.05 vs. vehicle, **p<0.001 vs. vehicle.
