Table 1. Characteristics of the study samples.
| Characteristics | Stroke sample (N=3313) |
MRI sample (N=1982) |
|---|---|---|
| Age (years) | 59.0±9.7 | 58.2±9.5 |
| Women (%) | 53.0 | 53.6 |
| Current smoking (%) | 14.9 | 13.3 |
| Diabetes mellitus (%) | 9.5 | 8.4 |
| Body mass index (kg/m2) | 27.9±5.1 | 27.7±5.0 |
| Systolic blood pressure (mm Hg) | 128±19 | 126±18 |
| Diastolic blood pressure (mm Hg) | 76±10 | 75±9 |
| Hypertension treatment (%) | 27.4 | 23.7 |
| Total cholesterol (mmol/L) | 5.3±1.0 | 5.3±0.9 |
| HDL cholesterol (mmol/L) | 1.3±0.4 | 1.3±0.4 |
| Cardiovascular disease (%) | 9.2 | 7.3 |
| Atrial fibrillation (%) | 3.0 | 1.9 |
| Average CO (ppm) | 7.0±6.3 | 6.7±6.0 |
| Average log CO (log ppm) | 1.7±0.6 | 1.7±0.6 |
| CO category 1 (≤4 ppm), (%) | 38.1 | 39.7 |
| CO category 2 (>4 to ≤5 ppm), (%) | 29.6 | 29.8 |
| CO category 3 (≥5 ppm), (%) | 32.3 | 30.5 |
| BNP (pg/mL), median (Q1, Q3)* | 8.3 (4.0, 18.7) | |
| CRP (mg/L), median (Q1, Q3)† | 2.0 (0.9, 4.6) | |
| MRI measures | ||
| TCBV (%) | 79.5±3.3 | |
| WMHV (%), median (Q1, Q3) | 0.05 (0.03, 0.09) | |
| SCI (%) | 10.9 |
HDL indicates high-density lipoprotein; CO, carbon monoxide; ppm, parts per million; BNP, B-type natriuretic peptide; CRP, C-reactive protein; TCBV, total cerebral brain volume; WMHV, white matter hyperintensity volume; SCI, silent cerebral infarct
Data are mean±SD (continuous variables) or percentages (categorical variables).
*
N=3296
†
N=3196