Figure 6.
Effects of LXA4 and ALX siRNA on the expression of FPR2, p38, IL-1β and IL-6 in cortex after SAH. LXA4 has no effects on protein level of FPR2 (A), but decreased the phosphorylation of p38 (B), and expression of IL-1β (C) and IL-6 (D). Silencing FPR2 by siRNA reduced the expression of FPR2 (A), abolished the effect of LXA4 on p38 (B), IL-1β (C) and IL-6 (D). n=6 for each group. #p<0.05 vs. SAH+vehicle, &p<0.05 vs. SAH+LXA4, %p<0.05 vs. SAH+LXA4+Scramble siRNA.