Table 5.
Axillary Ultrasound as a Predictor of Extent of Pathologic Nodal Disease Burden
| First author | No. with axillary US |
Pathologic nodal status by US results | p Value | ||
|---|---|---|---|---|---|
| Pathologic nodal status |
Negative US, n (%) |
Suspicious US, n (%) |
|||
| Kwak23* | 323 SLNB | pN0 | 129 (88) | 127 (72) | 0.002 |
| pN1 | 17 (12) | 35 (20) | |||
| pN2-3 | 1 (1) | 14 (8) | |||
| Abe19 | 559 | pN0 | 291 (77) | 69 (38) | |
| pN1 | 77 (20) | 62 (34) | |||
| pN2-3 | 10 (3) | 50 (28) | |||
| Damera24 | 166 | pN0 | 45 (71) | 57 (55) | |
| pN1 | 17 (27) | 27 (26) | |||
| pN2-3 | 1 (2) | 19 (18) | |||
| Hinson25 | 112† | pN0 | 37 (73) | 17 (28) | |
| pN1 | 14 (27) | 25 (41) | |||
| pN2-3 | 0 | 19 (31) | |||
| Nori26 | 132 | pN0 | 78 (77) | 12 (39) | |
| 1-2 positive nodes | 21 (21) | 13 (42) | |||
| >2 positive nodes | 2 (2) | 6 (19) | |||
| Current‡ | 242 | pN0 | - | - | 0.005 |
| 1-2 positive nodes | 160 (88) | 43 (70) | |||
| >2 positive nodes | 21 (12) | 18 (30) | |||
*
Axilla imaged with ultrasound, MRI, and/or PET scan. Abnormal nodes on any imaging modality included.
†
US performed on patients identified as being high risk for nodal metastasis based on grade III tumors, size ≥1 cm, or grade II and size ≥1.5 cm.
‡
All patients with a positive sentinel lymph node biopsy.
US, ultrasound; SLNB, sentinel lymph node biopsy.