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. 2015 Dec 10;4:e09460. doi: 10.7554/eLife.09460

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© 2015, Loh et al

This article is distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use and redistribution provided that the original author and source are credited.

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Figure 4. — Representative examples of baseline-subtracted traces of PER2-driven bioluminescence in the SCN (a), hippocampus (HP; b), and liver (c) explants from aligned (black) and misaligned (red) mice. (d) Phase relationship between the first calculated peaks of ex vivo bioluminescence plotted against time of the prior lighting cycle (ZT) shows a significant phase change in the HP and liver. (e) Period of bioluminescence rhythms were determined by sine wave fitting. (f) Damping rates were determined from 6 days in culture. *denotes significant differences (p < 0.05) between aligned and misaligned samples. Box and whisker plots display the median as a line, the 25th to 75th percentiles, and the 10th to 90th percentiles respectively.

DOI: http://dx.doi.org/10.7554/eLife.09460.009

Figure 4—source data 1. PER2-driven bioluminescence rhythms of mice subjected to aligned and misaligned feeding.
DOI: http://dx.doi.org/10.7554/eLife.09460.010

elife-09460-fig4-data1.xls^{(316.5KB, xls)}

DOI: 10.7554/eLife.09460.010