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Freehand drawing schematically representing tissue targets of CMR in acute myocarditis. A typical inferior-lateral left ventricular involvement with subepicardial spread is depicted. In most cases, the process derives from a viral infection that induces myocardial necrosis (or apoptosis) and triggers an immunoreactive response, with subsequent vasoactive phenomena and tissue oedema (freehand drawing by Bettina Conti, MD, Sapienza University of Rome)
