Fig. 1.

Illustration of the interaction network of immunogenic peptide fragments, High-risk HPV strains which contributed for the formation of these fragments and MHC class I alleles are shown. Edges with different colors represent various immunogenic peptide fragments as shown in figure legends. High-risk HPV strains are shown in green hexagon in the inner circle and HLA alleles on the outer circle with red color. From the figure it is clear that few alleles (e.g. A2602, A2603, A2902, A3002, B0702, B1502, B4002, B4501, B4801, B5401) are targeted by only one immunogenic peptide fragments, while majority of HLA alleles (A0201, A0202, A0203, A0206, A0211, A0212, A0216, A0219, A0250, A0301, A1101, A2301, A2402, A2403, A3001, A3101, A3201, A3301, A6801, A6802, A6901, B0801, B1501, B1503, B1517, B2705, B3501, B3901, B5301, B5801) are targeted by most of the immunogenic peptides selected in this study