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. 2015 Aug 29;291:271–283. doi: 10.1007/s00438-015-1105-8

Fig. 3.

Fig. 3

H3K56Ac is the critical target of HST3 deacetylase. All the strains shown carry deletions of both copies of the genes encoding histones H3 and H4 (hht1Δ-hhf1Δ and hht2Δ-hhf2Δ). The sole source of histones H3 and H4 in these strains is a plasmid carrying wild-type histone genes pHHT1-HHF1 (strains YIC335, YIC349), a plasmid carrying an H3 K56R substitution phht2K56R-HHF2 (YIC339, YIC351), or a plasmid carrying an H3 K56Q substitution phht2K56Q-HHF2 (YIC345, YIC350). The top row shows colonies of a wild-type HST3 strain transformed with each of the plasmids. The bottom row shows colonies of the hst3Δ strains transformed with each of the plasmids