Figure 8. CSF-c neurons sensitive to both fluid movement and lowered pH influence the spinal locomotor network as well as stretch receptor neurons.

(a) Ciliated CSF-c neurons respond to fluid movements and to lowered pH through activation of ASIC3. (b) Schematic illustration of a cross-section of the lamprey spinal cord, with a CSF-c neuron by the central canal (cc) and lateral axonal projections in the grey matter providing input to the locomotor network and projections in close apposition to a stretch receptor neuron at the spinal cord margin.