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Effects of treatment with sildenafil on autonomic tonus to the heart. (A) Effect of atropine blockade on resting HR (a, p < 0.01 vs. sham + vehicle; b, p < 0.05 vs. sham + sildenafil; c, p < 0.01 vs. 2K1C + vehicle). (B) Effect of propranolol blockade on resting HR (a, p < 0.01 vs. sham + vehicle; b, p < 0.01 vs. sham + sildenafil; c, p < 0.01 vs. 2K1C + vehicle).
