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. 2016 Jan 28;7:37. doi: 10.3389/fmicb.2016.00037

FIGURE 1.

FIGURE 1

Temperature-dependent Gm resistance of Francisella tularensis. F. tularensis Schu S4 (A) and LVS (B) showed increased resistance to gentamicin (Gm) at ambient temperature (26°C) compared to mammalian body temperature (37°C). Bacteria were cultivated in general growth media, suspended in PBS, and treated with Gm at the indicated temperature. Bacteria were diluted and plated for viable CFU at the indicated times. Plotted values represent mean CFU ± SD. Log-transformed data were analyzed using a two-way ANOVA and a Sidak’s multiple comparisons test. ∗P < 0.05 Schu S4 1 h 26°C vs. 37°C (A); LVS 1 h 26°C vs. 37°C Gm (500 μg/ml), 2 h 26°C vs. 37°C Gm (100 and 500 μg/ml; B).