Table 2.

Summary of the quality evaluation by Jadad scale of clinical trials of tolvaptan in patients with heart failure

Trials	Random sequence generation	Allocation concealment	Double blinding	Description of withdrawals and drop-out	Score
Gheorghiade 2003 [17]	2	2	1	1	7
Gheorghiade 2004 [18]	2	2	1	1	7
Gheorghiade 2007 [19]	2	2	1	1	7
Konstam 2007 [20]	2	1	1	1	6
Udelson 2007 [21]	2	2	1	1	7
Matsuzaki 2011 [22]	2	2	1	1	7
Matsuzaki 2011 [23]	2	2	1	1	7
Hauptamn 2013 [24]	2	1	1	1	6