. 2015 Dec 15;8(12):22217–22226.

Table 4.

The protein of HDAC2, PI3K, p-AKT expression in lung tissue by Western-blot and the integral optical density (IOD) by immunohistochemistry (x̅ ±s)

Group	n	Immunohistochemistry			Western-blot

		HDAC2	PI3K	p-AKT	HDAC2	PI3K	p-AKT
Healthy control group	10	90.05±2.38	21.22±2.19	23.76±1.26	0.636±0.032	0.193±0.013	0.225±0.085
COPD model group	10	18.06±1.27^*	99.15±6.85^*	104.43±5.69^*	0.115±0.014^*	0.745±0.029^*	0.786±0.067^*
Budesonide group	10	32.49±5.49^‡	76.43±3.32^‡	87.64±4.23^‡	0.201±0.098^**	0.632±0.035^**	0.699±0.049^**
Erythromycin group	10	53.33±3.24^†,^§	57.72±4.51^†,^§	64.38±3.79^†,^§	0.479±0.046^†,^§	0.458±0.038^†,^§	0.583±0.025^†,^§
Erythromycin + budesonide group	10	67.02±2.28^†,^§	44.83±2.67^†,^§	57.21±5.65^†,^§	0.501±0.037^†,^§	0.332±0.043^†,^§	0.417±0.087^†,^§

Compared with healthy control group, P<0.05;

^†

Compared with COPD model group, P<0.05;

^§

Compared with budesonide group, P<0.05;

^‡

Compared with COPD model group, P=0.145, 0.203, 0.178;

^**

Compared with COPD model group, P=0.423, 0.706, 0.693.