Table 2.
EGFR Mutation/HER2 Overexpression Status According to Demographics
| Variable/Categories | EGFR | HER2 | ||
|---|---|---|---|---|
|
|
|
|||
| Mutation N% | Wide-type N% | Positive N% | Negative N% | |
| Gender | ||||
| Male | 9/11.84 | 69/88.16 | 15/19.23 | 63/80.77 |
| Female | 3/9.09 | 30/90.9 | 9/27.27 | 24/72.72 |
| P | 0.497 | 0.243 | ||
| Age | ||||
| ≤65 | 6/7.41 | 75/92.59 | 15/19.23 | 63/80.77 |
| ≥65 | 6/20 | 24/80 | 9/27.27 | 24/72.72 |
| P | 0.065 | 0.243 | ||
| Ecog | ||||
| 0-1 | 5/7.14 | 65/92.86 | 9/15.79 | 48/84.21 |
| 2-3 | 7/17.07 | 34/82.93 | 15/27.78 | 39/72.22 |
| P | 0.065 | 0.065 | ||
| Histology | ||||
| Ade | 12/26.67 | 33/73.33 | 18/40 | 27/60 |
| No-Ade | 0/0 | 66/100 | 6/9.09 | 60/90.9 |
| P | 0.000 | 0.000 | ||
| Smoking History | ||||
| Never Smoker | 6/15.38 | 33/84.62 | 15/23.81 | 48/76.19 |
| Smoker | 6/8.33 | 66/91.67 | 9/18.75 | 39/81.25 |
| P | 0.204 | 0.344 | ||
| Stage | ||||
| IIIB | 4/8.88 | 41/91.11 | 9/15.79 | 48/84.21 |
| IV | 8/12.12 | 58/87.87 | 15/27.78 | 39/72.22 |
| P | 0.417 | 0.096 | ||
Note: ECOG Eastern Cooperative Oncology Group, Ade adenocarcinoma.