Table 1.
Physiological and biochemical properties
| Vehicle | DIOP | Curcumin | |
|---|---|---|---|
| Body weight (g) | 25.5 ± 3.8 | 34.2 ± 4.5* | 26.3 ± 3.7# |
| Serum Ca (mg/dL) | 10.21 ± 0.46 | 9.89 ± 0.41 | 10.57 ± 0.55 |
| Urine Ca/Cre (mg/mg) | 0.069 ± 0.007 | 0.126 ± 0.014* | 0.073 ± 0.009# |
| TRACP-5b (pg/mL) | 2.48 ± 0.32 | 3.92 ± 0.44* | 2.83 ± 0.37# |
| OCN (ng/mL) | 479 ± 50.8 | 315 ± 32.4* | 506 ± 59.2# |
| CTX (ng/mL) | 37.7 ± 6.8 | 74.7 ± 8.9* | 48.2 ± 9.2# |
Values are expressed as mean ± SD, n = 8-10 in each group.
*
P < 0.05, versus vehicle group;
#
P < 0.05, versus GIOP group.
Ca, calcium; Cre, creatinine; TRACP-5b, tartrate resistant acid phosphatase-5b; OCN, osteocalcin; CTX, C-terminal telopeptide of type I collagen.