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. 2015 Dec 1;8(12):15801–15807.

Table 2.

Correlation between TAK1/TAB1 expression and clinicopathological grading of non-small cell lung carcinoma

Group Total cases TAK1 P TAB1 P


Positive cases Negative cases Positive cases Negative cases
Gender 0.21 0.88
    Male 54 32 22 28 26
    Female 20 15 5 10 10
Age (year) 0.37 0.24
    <65 38 26 12 17 21
    ≥65 36 21 15 21 15
Degree of differentiation 0.61 0.79
    Low 18 13 5 10 8
    Moderate 29 20 9 16 13
    High 17 14 3 11 6
Clinical stage 0.0002 <0.0001
    I, II 39 17 22 11 28
    III, IV 35 30 5 27 8
Lymph node metastasis 0.005 0.001
    Yes 43 33 10 29 14
    No 31 14 17 9 22
Smoking 0.32 0.97
    Yes 41 24 17 21 20
    No 33 23 10 17 16
Tumor size (cm) 0.58 0.24
    <3 38 23 15 17 21
    ≥3 36 24 12 21 15

TAK1: transforming growth factor beta-activated kinase 1; TAB1: TAK1-binding protein 1.