Table 2.
Serum ALT at different time points in 4 groups (x±s)
| Group | n | ALT(U/L) | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| Before | 24 h | 48 h | 72 h | 96 h | 1 w | ||
| MSCs | 12 | 36.8±7.4 | 33.4±8.3 | 34.5±3.7 | 40.4±4.8 | 38.5±9.2 | 35.9±6.4 |
| ALF | 12 | 36.3±7.8 | 1157.5±282.4 | 1673.4±399.5 | 495.1±134.2 | 190.6±60.3 | 59.8±10.4 |
| T | 12 | 34.5±6.6 | 1239.7±275.3 | 847.5±202.1a | 148.5±54.6a | 82.5±28.7a | 38.3±10.3a |
| H | 12 | 36.0±9.0 | 1296.2±264.6 | 955.0±266.1a | 197.2±64.2a | 98.0±22.3a | 37.5±11.6a |
a
P<0.05 vs. ALF group.
hUCMSCs transplantation was conducted at 24 h after establishment of animal model. ALF: acute liver failure, T: tail vein transplantation; H: intrahepatic transplantation; MSCs: mesenchymal stem cells.