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. 2015 Dec 1;8(12):16081–16088.

Table 2.

Multivariate for overall survival and progression-free survival of clinical, histopathological and immunohistochemical parameters

Characteristics		Overall survival		Progression free survival

		HR [95% CI]	P-values	HR [95% CI]	P-values
pTMN stage	I, II	1		1
pTMN stage	III	1.82 [1.25-2.79]	0.012^*	1.75 [1.21-3.16]	0.017^*
Lymph node metastasis	No	1		1
Lymph node metastasis	Yes	1.41 [1.02-3.54]	0.045^*	1.69 [1.15-4.26]	0.039^*
p-Akt expression	Negative	1		1
p-Akt expression	Positive	1.52 [1.06-3.76]	0.041^*	1.63 [1.04-3.44]	0.034^*
VEGF expression	Negative	1		1
VEGF expression	Positive	1.45 [0.91-4.64]	0.146	1.47 [1.02-3.75]	0.028^*
NOB1 expression	Low	1		1
NOB1 expression	High	1.55 [0.96-3.22]	0.091	1.71 [0.95-3.79]	0.111
Gene-based risk score		1.21 [1.04-1.56]	0.037^*	1.19 [1.02-1.79]	0.041^*

^*

P<0.05;

HR: hazard ratio; CI: confidence interval.