. Author manuscript; available in PMC: 2016 Jan 28.

Published in final edited form as: Int J Tuberc Lung Dis. 2014 Aug;18(8):912–918. doi: 10.5588/ijtld.13.0028

Table 1.

Treatment regimens for MDR LTBI, Chuuk, Federated States of Micronesia, 2009–2012^*

Source patient isolate	MDR LTBI treatment regimen
M. tuberculosis resistant to INH, RMP and ETH	Adults aged >12 years: MFX 400 mg by mouth daily and EMB 15 mg/kg by mouth daily for 12 months Children aged ≤12 years: LVX 20 mg/kg by mouth daily and EMB 15 mg/kg by mouth daily for 12 months
M. tuberculosis resistant to INH, RMP, PZA, EMB and SM	Adults aged >12 years: MFX 400 mg by mouth daily for 12 months Children aged ≤12 years: LVX 20 mg/kg by mouth daily and ETH 20 mg/kg by mouth daily for 12 months

Regimens were recommended by the MDR-TB Expert Network, a group of US national TB experts who convene every 2 months to offer expert opinion on the treatment and management of challenging drug-resistant cases.

MDR=multidrug-resistant; LTBI=latent tuberculous infection; INH=isoniazid; RMP=rifampin; ETH=ethionamide; MFX=moxifloxacin; EMB=ethambutol; LVX= levofloxacin; PZA = pyrazinamide; SM = streptomycin.