Table 1. The levels of cross-NAb and survival rates in JEV vaccines-immunized BALB/c mice.

Types	Groups	Neutralizing antibody titersa	P		Survival %b (No. of survivors/No. of challenged)	P
DENV1	INV	1:30	0.006c	0.018d	40(4/10)	0.612c	0.007d
	LAV	1:113	—	0.002e	50(5/10)	—	0.002e
	PBS	<1:10	—	—	0(0/10)	—	—
DENV2	INV	1:403	0.003c	0.002d	60(6/10)	0.434c	0.000d
	LAV	1:74	—	0.000e	50(5/10)	—	0.006e
	PBS	<1:10	—	—	0(0/10)	—	—
DENV3	INV	1:23	0.000c	0.000d	43(3/7)	0.245c	0.435d
	LAV	1:59	—	0.000e	67(6/9)	—	0.043e
	PBS	<1:10	—	—	25(2/8)	—	–
DENV4	INV	1:17	0.028c	0.006d	80(8/10)	0.146c	0.000d
	LAV	1:71	—	0.018e	100(10/10)	—	0.000e
	PBS	<1:10	—	—	0(0/10)	—	—

^aThe geometrical mean neutralizing antibody titers in sera of pre-challenged mice.

^bMice were challenged i.c. with DENVs 3 weeks after the final immunization, and then monitored daily for 28 days. The survival rates were determined as 100 × (number of survivors)/(numbers of challenged).

^cP value was calculated between INV and LAV.

^dP value was calculated between INV and PBS.

^eP value was calculated between LAV and PBS.