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. 2016 Jan 28;6:19899. doi: 10.1038/srep19899

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Copyright © 2016, Macmillan Publishers Limited

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Asterisks marked the COG categories in treated samples that had a significantly different COG distribution from the background composition of the E. coli genome (with confidence level of 0.99 and bootstrap replicates of 10000). Key for the various COG functional categories are as described in Fig. 4, with additional categories as follows: U: Intracellular trafficking, secretion, and vesicular transport; X: mobilome, phages, and transposons.