Skip to main content
. 2015 Dec 22;17(1):7. doi: 10.3390/ijms17010007

Figure 6.

Figure 6

Schematic representation of possible mechanism by which lignan phenolic SDG (LGM2605) protects lung cells against radiation exposure. SDG upregulates the phase II cytoprotective enzymes, HO-1, NQO1 and the gene levels of GSTM1; thus, when the non-malignant lung cells are exposed to ionizing radiation, less oxidative damage is induced, leading to increased clonogenic survival of the irradiated cells.