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. 2015 Dec 23;17(1):11. doi: 10.3390/ijms17010011

Figure 7.

Figure 7

The transcription factor CEBPB suppressed FGF21 expression by binding to FGF21 promoter. QRT-PCR analysis showed CEBPB reduced FGF21 mRNA level. ** for 0.001 < p < 0.01 (A); The electrophoretic mobility shift assay (EMSA) was used to simulate the binding of CEBPB with FGF21 promoter in vitro (B); The chromatin immunoprecipitation (CHIP) assay was performed to detect the binding of CEBPB with FGF21 promoter in vivo (C), total chromatin and normal mouse IgG were used as the input and the negative control respectively.