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. 2015 Dec 24;17(1):18. doi: 10.3390/ijms17010018

Figure 5.

Figure 5

CHMP4C acts downstream of Aurora B. (A) Expression of Aurora B and CHMP4C after Aurora B or CHMP4C knockdown in A549 and H1299 cells; (B) The phosphorylation level of CHMP4C in untreated and AZD1152 treated (10 and 1000 nM) A549 and H1299 cells; (C) The phosphorylation level of CHMP4C in untreated and AZD1152 treated (100 nM) A549 and H1299 cells; (D) Western blot analysis of CHMP4C phosphorylation level in A549 and H1299 cells transfected with pCDNA3.1-Aurora B; (E) The mRNA expression level of CHMP4C or Aurora B was quantitated with real-time PCR (mean ± S.E., n = 3) after the A549 and H1299 cells undergone transfection of negative control or siAurora B.