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. 2016 Jan 8;17(1):74. doi: 10.3390/ijms17010074

Figure 5.

Figure 5

Model of cytoskeletal interactions with components of innate immunity. Microbial infection creates perturbations in cytoskeletal interactions or actin polymerization that function as sensors to activate the innate immune response. The IFNβ and inflammasome pathways are key targets. Solid arrows denote direct interactions and dashed arrows signify that intermediary steps occur.