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. 2016 Jan 12;17(1):89. doi: 10.3390/ijms17010089

Table 1.

Evaluation of in vivo tumor formation after sub-cutaneous injection of human keratinocytes infected with retroviral vector expressing Ha-RasG12V and IκBαM in presence or in absence of endogenous survivin.

Condition Tumour at 4 Weeks Tumour at 6 Weeks Tumour Size (cm3 ± SD)
NoLacZ Scramble − (3/3) + (3/3) 0.49 ± 0.17
NoLacZ Survivin siRNA − (3/3) + (3/3) 0.39 ± 0.14
RasG12V-IκBαM Scramble + (3/3) + (3/3) 0.89 ± 0.33
RasG12V-IκBαM Survivin siRNA − (3/3) + (3/3) 1.01 ± 0.38