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. Author manuscript; available in PMC: 2016 Jan 28.
Published in final edited form as: Dev Neurobiol. 2007 Feb 1;67(2):158–172. doi: 10.1002/dneu.20339

Figure 5.

Figure 5

Regeneration in NT-4/5 knockout mice. Mice homozygous null for the NT-4/5 gene were mated with thy-1-YFP-H mice and then back crossed until offspring that were both NT-4/5−/− and YFP+ were identified. The common fibular nerves of these mice were cut and repaired using grafts obtained either from NT-4/5−/− mice that were YFP− or wild type (NT-4/5+/+ and YFP−) mice. Cumulative frequency distributions of axon profile lengths measured in these unstimulated mice are shown in panel A. The format is the same as that of figure 2. In panel B, data are shown in a similar format from measurements of axon profile lengths in a set of these animals in which the repaired nerve was electrically stimulated. Inset is a graph of average median axon profile lengths (+SEM) for these four treatment groups.