Table 2.
Levels of biochemical indexes for family members exposed and not exposed to arsenic a.
| Biochemical Variables | Overall (n = 25) | Individuals Exposed to Arsenic (n = 12) | Individuals Unexposed to Arsenic (n = 13) | p-Value |
|---|---|---|---|---|
| ALT (U/L) | 22.0 (16.0, 30.0) | 27.5 (17.0, 30.8) | 18.0 (13.0, 26.0) | 0.185 |
| AST (U/L) | 34.0 (31.0, 38.0) | 37.5 (33.0, 42.5) | 31.0 (29.0, 34.0) | 0.006 |
| γ-GT (U/L) | 14.0 (11.0, 34.0) | 25.5 (13.3, 77.0) | 12.0 (9.0, 19.0) | 0.021 |
| Creatinine (mg/dL) | 102.0 (77.1, 163.1) | 156.5 (108.7, 167.0) | 77.4 (62.9, 127.7) | 0.012 |
| UA (μmol/L) | 286.0 (201.0, 395.0) | 353.5 (249.5, 396.5) | 237.0 (183.0, 286.0) | 0.074 |
| Glu (mmol/L) | 4.1 (3.8, 4.5) | 4.1 (3.8, 4.7) | 4.1 (3.6, 4.4) | 0.518 |
| HbA1c (%) | 5.8 (5.7, 6.1) | 6.1 (5.7, 6.1) | 5.8 (5.5, 6.0) | 0.245 |
| TG (mmol/L) | 1.5 (1.0, 1.6) | 1.4 (1.0, 1.6) | 1.5 (1.0, 1.8) | 0.667 |
| TC (mmol/L) | 4.2 (3.9, 4.8) | 4.2 (3.8, 5.6) | 4.2 (4.0, 4.7) | 0.580 |
| HDL-C (mmol/L) | 1.3 (1.2, 1.5) | 1.4 (1.2, 1.5) | 1.3 (1.2, 1.5) | 0.599 |
| LDL-C (mmol/L) | 1.8 (1.6, 2.4) | 1.7 (1.6, 2.9) | 1.9 (1.6, 2.1) | 0.902 |
| Hcy (μmol/L) | 14.0 (13.4, 16.8) | 15.2 (13.7, 17.7) | 13.7 (12.6, 16.2) | 0.166 |
Notes: the data are expressed as the median (25th, 75th). Abbreviations: ALT, alanine aminotransferase; AST, aspartate aminotransferase; γ-GT, γ-glutamyl transpeptidase; UA, uric acid; Glu, glucose; HbA1c, glycated hemoglobin; TG, triglyceride; TC, total cholesterol; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; Hcy, homocysteine. a The Mann-Whitney U test was performed to analyze the differences in these biochemical indexes between the subjects with and without arsenic exposure in the family.