Table 1.
Intake (default) parameters for adult ASGM miners used in the human health risk assessment from the RISC 4.02 software [23,25].
Parameter | Central Tendency Exposure (CTE) | Reasonable Maximum Exposure (RME) | ||||||
---|---|---|---|---|---|---|---|---|
As | Cd | Pb | Hg | As | Cd | Pb | Hg | |
Averaging Time (Life time)/years | 70 | 70 | 70 | 70 | 70 | 70 | 70 | 70 |
Body Weight/kg | 58.6 | 58.6 | 58.6 | 58.6 | 58.6 | 58.6 | 58.6 | 58.6 |
Oral Exposure Frequency for sediment (events/year) | 40 | 40 | 40 | 40 | 350 | 350 | 350 | 350 |
Dermal Exposure Duration for sediment (year) | 9 | 9 | 9 | 9 | 30 | 30 | 30 | 30 |
Oral Exposure Frequency for water (events/year) | 40 | 40 | 40 | 40 | 350 | 350 | 350 | 350 |
Oral Exposure Duration for water (year) | 9 | 9 | 9 | 9 | 30 | 30 | 30 | 30 |
Ingestion rate for water (L/day)—IRwo | 2 | 2 | 2 | 2 | 6 | 6 | 6 | 6 |
Ingestion rate for sediment (mg/day)—IRsed | 40 | 40 | 40 | 40 | 100 | 100 | 100 | 100 |
Total skin surface area (cm2)—SA | 18,400 | 18,400 | 18,400 | 18,400 | 23,000 | 23,000 | 23,000 | 23,000 |
Fraction of skin exposed to sediment (unitless) | 0.11 | 0.11 | 0.11 | 0.11 | 0.25 | 0.25 | 0.25 | 0.25 |
Sediment-skin adherence factor (mg/cm2) | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 |
Oral cancer slope factor (1/mg/kg—day) | 1.5 | 0.014 | - | - | 1.5 | 0.014 | - | - |
Dermal cancer slope factor (1/mg/kg—day) | 1.5 | 0.014 | - | - | 1.5 | 0.014 | - | - |
Oral reference dose (mg/kg—day) | 0.0003 | 0.0005 | 0.0036 | 0.0003 | 0.0003 | 0.0005 | 0.0036 | 0.0003 |
Dermal reference dose (mg/kg—day) | 0.0003 | 0.0005 | 0.0036 | 0.0003 | 0.0003 | 0.0005 | 0.0036 | 0.0003 |
Oral-sediment absorption adjustment factor (unit less) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Dermal-sediment absorption adjustment factor (unit less) | 0.03 | 0.001 | 0.01 | 0.1 | 0.03 | 0.001 | 0.01 | 0.1 |
Oral-water absorption adjustment factor (unit less) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Dermal-water absorption adjustment factor (unit less) | 1 | 1 | 1 | 1 | 1 | 1 | 1 | 1 |
Skin permeability coefficient (cm/hr) | 0.001 | 0.001 | − | 0.0017 | 0.001 | 0.001 | − | 0.0017 |