FIG 6.

Expression of PLA2G2A in L. monocytogenes-infected C3H/HeJ mice. PLA2G2A-functional C3H/HeJ mice were infected with L. monocytogenes, and expression of IL-22 and PLA2G2A was analyzed. (A) Expression of IL-22 and PLA2G2A was analyzed by RT-PCR before and on days 1, 2, and 5 after L. monocytogenes infection. Each group consisted of 3 mice. *, P < 0.05 between the indicated groups. (B) Correlation of IL-22 and PLA2G2A expression of the liver. Individual RT-PCR data for livers from uninfected mice (day 0) and L. monocytogenes-infected mice on days 1, 2, and 5 are plotted. (C) The livers of uninfected mice (day 0) or L. monocytogenes-infected mice on day 1 were stained with anti-PLA2G2A Ab (red) and DAPI (blue) and analyzed by confocal laser scanning microscopy with a 60× objective and 3× zoom.