FIG 2.

Lung CD4⁺ T cells upregulate IFN-γ expression but not IL-10 during low-dose T. muris infection. (A and B) Frequencies of CD4⁺ lymphocytes expressing IFN-γ (A) and IL-10 (B) in the lung ex vivo after polyclonal stimulation. (C) mRNA expression of Tbx21, Ifng, and Il10 (relative to Actb) in IFN-γ⁺ and IFN-γ⁻ lung CD4⁺ T cells from GREAT mice sorted by fluorescence-activated cell sorting. Data are means ± SEM, representative of 3 independent experiments (n = 3 to 5 mice per experiment) (A and B) or representative of 2 independent experiments (n = 3 mice per experiment) (C). Ctrl, control; Tm, T. muris infected; ns, not significant; Rel., relative.