Table 2.
Patients receiving invasive procedures, time to management decision, and diagnostic procedures for the Pre-EBUS cohort compared to the Post-EBUS cohort
| Pre-EBUS cohort (n = 234) | Post-EBUS cohort (n = 326) | p | |
|---|---|---|---|
| n (%)a | n (%)a | ||
| Invasive procedures | |||
| Bronchoscopy | 135 (57.7) | 131 (40.2) | <0.001** |
| CT-TTNA | 92 (39.3) | 95 (29.1) | 0.012* |
| EBUS | 0 (0) | 90 (27.6) | <0.001** |
| Thoracentesis | 26 (11.1) | 24 (7.4) | 0.125 |
| Other invasive procedures | 30 (12.8) | 47 (14.4) | 0.588 |
| Other surgical procedures | 9 (3.8) | 13 (4.0) | 0.932 |
| Mediastinoscopy | 1 (0.4) | 3 (0.9) | 0.644d |
| Time to management decisionc | |||
| ≤ 28 days | 154 (66.7) | 245 (75.9) | |
| > 28 days | 77 (33.3) | 78 (24.1) | 0.018* |
| Median (IQR) | Median (IQR) | ||
| Time to management decision (days)c | 17 (24) | 13 (21) | 0.070d |
| Number of invasive diagnostic proceduresb | 1 (0) | 1 (0) | 0.842e |
Thoracentesis: thoracentesis, pleural effusion drainage, pleural biopsy
Other invasive procedures: FNA, US-FNA, EUS-FNA, biopsy other, CT biopsy other
Other surgical therapeutic/diagnostic procedures: surgery for brain metastasis, bone marrow trephine, spinal lesions
*p < 0.05, **p < 0.01
aNumber of patients
bNumber per patient
cExcludes 6 patients with no date of presentation available – unable to establish time to management decision
dFisher’s exact test
eMann–Whitney U test; all other tests except d are Pearson’s chi squared test