. 2016 Jan 27;16:42. doi: 10.1186/s12885-016-2073-z

Table 5.

Management of oral mucositis

Systemic	Topical
1. Pain management	Diluting agents^b: Saline, bicarbonate rinses, frequent water rinses, dilute hydrogen peroxide rinses
• Analgesics: WHO ladder	Topical anaesthetics^b: Dyclonine HCl, xylocaine HCl, benzocaine HCl, diphenhydramine HCl
• Adjuncts: Relaxation, imagery, biofeedback, hypnosis and transcutaneous electrical nerve stimulation
	Analgesic agents^b: Benzydamine HCl
• Beta-carotene	Analgesic agents^b: Benzydamine HCl
• Beta-carotene	Coating agents^c: Kaolin-pectin, aluminium chloride, aluminium hydroxide, magnesium hydroxide, hydroxypropyl cellulose, sucralfate
2. Radioprotectors^a
2. Radioprotectors^a	Lip Lubricants^c: Water-based lubricants, lanolin
• Amifostine: Scavenge free radicals
3. Biologic Response Modifiers^a
• G-CSF, GM-CSF, Keratinocyte Growth Factor

^aMore relevant in Bone Marrow Transplant cases and not crucial in radiotherapy patients

^bMost practiced and accepted form of topical therapy

^cThough mentioned in-frequently in literature and case discussions, they have failed to generate sufficient impact in routine practice