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. 2016 Jan 27;14:27. doi: 10.1186/s12967-016-0776-1

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© Strong et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Calvarial defects treated with lnASC- or obASCs-seeded scaffolds display reduced osteoclastic activity. Calvarial defects were created in the parietal bone of nude mice. Histology was conducted 2 weeks post operatively. a Representative images of sections stained with TRAP, allowing osteoclasts to appear bright red. b Quantification of TRAP stain. Bars, ± SEM. ***, P < 0.001, compared to defects treated with neither scaffolds or cells; ^#, P < 0.05, compared between defects treated with scaffold and scaffolds seeded with lnASCs