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. 2016 Jan 28;18:14. doi: 10.1186/s13058-016-0674-8

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© Xu et al. 2016

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 6 — Expression patterns of Tiam1 and OPN in breast cancer-associated fibroblasts, correlated with invasiveness. Representative sections of non-invasive (DCIS) and invasive breast cancers showing tumor cells (T) with interspersed stroma (S), stained with hematoxylin and eosin (H&E), Tiam1 antibody, or OPN antibody as indicated. a and b White arrows indicate fibroblast nuclei in stroma adjacent to tumor cells. c and f Green arrows indicate fibroblasts with detectable overexpression of indicated protein. d and e Red arrows indicate fibroblasts without overexpression of indicated protein. All images taken at 40× magnification, scale bar indicates 100 μM