Table 1.
Biophysical measures in CA1 pyramidal neurons that were not altered by the high-fat diet (HFD) in young adult male and female rats
| Rats (n) | Neurons (n) | Input resistance (MΩ) | Sag (mV) | Resting potential (mV) | |
|---|---|---|---|---|---|
| Control male | |||||
| aCSF | 22 | 23 | 81.0 ± 2.4 | 8.3 ± 0.6 | −70.2 ± 0.3 |
| Insulin | 15 | 85.9 ± 3.0 | 10.2 ± 0.1 | −66.0 ± 1.3 | |
| HFD male | |||||
| aCSF | 14 | 24 | 66.7 ± 2.3 | 8.1 ± 0.6 | −67.5 ± 0.6 |
| Insulin | 13 | 64.3 ± 3.5 | 8.9 ± 1.0 | −68.7 ± 0.4 | |
| Control female | |||||
| aCSF | 7 | 14 | 59.6 ± 3.4 | 4.6 ± 0.8 | −71.6 ± 0.4 |
| Insulin | 8 | 53.6 ± 1.2 | 7.1 ± 0.9 | −66.7 ± 0.6 | |
| HFD female | |||||
| aCSF | 14 | 20 | 85.5 ± 4.8 | 6.5 ± 0.5 | −70.3 ± 0.4 |
| Insulin | 9 | 87.0 ± 6.9 | 10.1 ± 2.2 | −63.3 ± 1.7 |