Table 1. Differences in relative content of lipids, α helix protein, aggregated β sheet protein, and lactate as determined from second derivatives of FTIR band intensities for hemorrhaged inner white matter (WM HM), nonhemorrhaged inner white matter (WM), granular layer (GL), and molecular layer (ML) from CM and sham, mild malaria anemia (MMA), and severe malaria anemia (SMA) mice.
Bold indicates a statistically significant difference (P < 0.05), relative to sham animals.
| Sample | 1742 cm−1 (lipid) | 1656 cm−1 (α helix protein) | 1625 cm−1 (aggregated β sheet protein) | 1127 cm−1 (lactate) | |
| CM WM HM | Average | −2.5 × 10−4 | −2.6 × 10−3 | 2.3 × 10−4 | 1.3 × 10−5 |
| SD | 1.1 × 10−5 | 3.5 × 10−4 | 3.0 × 10−5 | 2.0 × 10−6 | |
| CM WM | Average | −6.6 × 10−4 | −1.8 × 10−3 | 3.0 × 10−4 | 6.6 × 10−5 |
| SD | 4.5 × 10−5 | 3.5 × 10−4 | 9.8 × 10−6 | 3.3 × 10−5 | |
| Control (sham) WM | Average | −7.2 × 10−4 | −1.8 × 10−3 | 3.6 × 10−4 | 9.1 × 10−5 |
| SD | 5.2 × 10−5 | 1.6 × 10−4 | 5.9 × 10−5 | 1.9 × 10−5 | |
| Control (MMA) WM | Average | −6.9 × 10−4 | −1.8 × 10−3 | 3.3 × 10−4 | 8.7 × 10−5 |
| SD | 2.5 × 10−5 | 2.6 × 10−4 | 2.7 × 10−5 | 1.4 × 10−5 | |
| Control (SMA) WM | Average | −7.0 × 10−4 | −1.8 × 10−3 | 3.4 × 10−4 | 8.6 × 10−5 |
| SD | 3.5 × 10−5 | 3.0 × 10−4 | 4.3 × 10−5 | 1.3 × 10−5 | |
| CM GL | Average | −2.4 × 10−4 | −2.0 × 10−3 | 2.5 × 10−4 | 6.0 × 10−5 |
| SD | 2.2 × 10−5 | 1.7 × 10−4 | 1.9 × 10−5 | 6.6 × 10−6 | |
| Control (sham) GL | Average | −2.4 × 10−4 | −2.1 × 10−3 | 3.0 × 10−4 | 5.0 × 10−5 |
| SD | 2.5 × 10−5 | 2.7 × 10−4 | 8.8 × 10−6 | 2.0 × 10−5 | |
| Control (MMA) GL | Average | −2.4 × 10−4 | −2.1 × 10−3 | 2.9 × 10−4 | 6.0 × 10−5 |
| SD | 3.0 × 10−5 | 2.7 × 10−4 | 1.5 × 10−5 | 3.3 × 10−5 | |
| Control (SMA) GL | Average | −2.6 × 10−4 | −2.1 × 10−3 | 2.7 × 10−4 | 5.5 × 10−5 |
| SD | 2.9 × 10−5 | 2.7 × 10−4 | 9.8 × 10−6 | 2.5 × 10−5 | |
| CM ML | Average | −1.6 × 10−4 | −2.1 × 10−3 | 2.7 × 10−4 | 4.0 × 10−5 |
| SD | 4.0 × 10−4 | 1.9 × 10−4 | 2.5 × 10−5 | 2.9 × 10−6 | |
| Control (sham) ML | Average | −3.5 × 10−5 | −2.1 × 10−3 | 2.9 × 10−4 | 4.1 × 10−5 |
| SD | 3.4 × 10−4 | 1.9 × 10−4 | 4.2 × 10−5 | 6.2 × 10−6 | |
| Control (MMA) GL | Average | −4.1 × 10−4 | −2.1 × 10−3 | 3.0 × 10−4 | 4.1 × 10−5 |
| SD | 7.5 × 10−5 | 2.0 × 10−4 | 4.2 × 10−5 | 3.0 × 10−6 | |
| Control (SMA) ML | Average | −2.3 × 10−4 | −2.2 × 10−3 | 2.7 × 10−4 | 3.8 × 10−5 |
| SD | 3.9 × 10−4 | 1.6 × 10−4 | 1.1 × 10−5 | 5.7 × 10−6 |