Table 1. Reagents and antibodies used in the experiments.

Reagents/antibodies	Manufacturers	City/country	Catalog no.	Source
FBS	Gibco	New York, US	10099-141	Bovine
Caspase-3 p17 antibody	Santa Cruz	Santa Cruz, CA	sc-98785	Rabbit
Akt antibody	Cell signaling	Beverly, MA	2920	Mouse
p-Akt antibody	Cell signaling	Beverly, MA	12694	Mouse
GAPDH	Proteintech	Wuhan, China	10494-1-AP	Rabbit
IL-1β	Peprotech	Rocky Hill, NJ	400-01B	Rat
Secondary antibodies	Proteintech	Wuhan, China	SA00001	Goat
Resveratrol	Sigma-Aldrich	St. Louis, MO	R5010	Grape skin
Trypsin	Sigma-Aldrich	St. Louis, MO	T4049	Porcine
Collagenase type II	Sigma-Aldrich	St. Louis, MO	C2139	Rat
17β-estradiol	Sigma-Aldrich	St. Louis, MO	491187	N/A
DMSO	Solarbio	Beijing, China	D8372-100	N/A
DMEM/F12	Gibco	New York, US	11320-033	N/A
TUNEL detection kit	Promega	Madison, WI	G3250	N/A
MTS Reagent Solution	Promega	Madison, WI	G3582	N/A
Caspase-3 activity kit	Beyotime	Shanghai, China	C1115	N/A
LY294002	Selleck Chemicals	Huston, TX	S1105	N/A
ICI182,780	Selleck Chemicals	Huston, TX	S1191	N/A
PE Annexin V Apoptosis	BD Pharmingen	San Jose, CA	559763	N/A
Detection Kit I