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Effect of treatment with metabolites 1−3 isolated from N. leucantha in bone marrow-derived macrophages (BMDMs) infected with L. donovani parasites. MØ (macrophages); MØI (infected macrophages); MØ+LPS (macrophages plus LPS); MØI+LPS (infected macrophages plus LPS). IL-6 (A) and IL-10 (B) cytokines levels were measured by ELISA in supernatant from BMDMs treated for 72 h. Mean cytokine level was expressed as pg/mL ± SE.
