Table 2. Estimated Proportion of Agreement in Metastatic Lesion Detection Between PET and CIM, Accounting for Intrapatient Clustering Effects by GEE Regression Model Analysis.

Modality			All patients				HNPC patients				CRPC patients
PET	CT	BS	All lesions	Lymph node lesions	Bone lesions	Visceral lesions	All lesions	Lymph node lesions	Bone lesions	Visceral lesions	All lesions	Lymph node lesions	Bone lesions	Visceral lesions
P	N/E	_	0.30 (0.17–0.48)	0.39 (0.21-0.62)	0.24 (0.11–0.46)	0.18 (0.06–0.42)	0.40 (0.20–0.65)	0.33 (0.08–0.73)	0.34 (0.12–0.67)	0.23 (0.07–0.56)	0.22 (0.10–0.42)	0.50 (0.45–0.54)	0.16 (0.05–0.42)	0.12 (0.02–0.49)
P	_	N/E	0.44 (0.28–0.61)	NA	0.22 (0.12–0.36)	NA	0.55 (0.32–0.76)	NA	0.28 (0.12–0.52)	NA	0.31 (0.14–0.57)	NA	0.18 (0.07–0.38)	NA
P	N/E*		0.44 (0.28–0.61)	0.90 (0.75–0.96)	0.22 (0.12–0.36)	0.41 (0.17–0.69)	0.55 (0.32–0.76)	0.84 (0.44–0.97)	0.28 (0.12–0.52)	0.39 (0.11–0.77)	0.31 (0.14–0.57)	0.93 (0.83–0.97)	0.18 (0.07–0.38)	0.42 (0.12–0.80)
N/E	P	_	0.07 (0.04–0.14)	0.07 (0.01–0.39)	0.09 (0.05–0.17)	0.05 (0.01–0.28)	0.06 (0.01–0.24)	0.17 (0.02–0.63)	0.07 (0.02–0.21)	0.00 (0.00–0.00)	0.08 (0.04–0.16)	0.00 (0.00–0.00)	0.10 (0.04–0.21)	0.08 (0.01–0.46)
N/E	_	P	0.03 (0.01–0.08)	NA	0.05 (0.02–0.12)	NA	0.03 (0.01–0.19)	NA	0.06 (0.01–0.29)	NA	0.03 (0.01–0.08)	NA	0.04 (0.02–0.11)	NA
N/E	P*		0.08 (0.04–0.16)	0.07 (0.01–0.39)	0.10 (0.06–0.18)	0.05 (0.01–0.28)	0.07 (0.01–0.27)	0.17 (0.02–0.63)	0.08 (0.02–0.27)	0.00 (0.00–0.00)	0.09 (0.05–0.17)	0.00 (0.00–0.00)	0.11 (0.06–0.21)	0.08 (0.01–0.46)

^*Combined CIM (CT and BS).

P = positive; N/E = negative/equivocal; NA = not applicable.

Data in parentheses are 95% CIs.