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. 2015 Jul 27;88(1054):20150185. doi: 10.1259/bjr.20150185

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© 2015 The Authors. Published by the British Institute of Radiology

This is an Open Access article distributed under the terms of the Creative Commons Attribution–NonCommercial 4.0 Unported License http://creativecommons.org/licenses/by-nc/4.0/, which permits unrestricted non-commercial reuse, provided the original author and source are credited.

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Figure 2. — Radiometal complexes for single photon emission CT and positron emission tomography imaging of nanoparticles (NPs). Chemical structures of ligands used for radiolabelling using metal isotopes. These ligands have been used to chelate radioisotopes to be covalently conjugated to the NP surface, or to encapsulate activity within particles. BAT, 6-[p-(bromoacetamido)benzyl]-1,4,8,11-tetraazacyclotetradecane-N,N′,N″,N‴-tetraacetic acid; CHX-DTPA, N-(2-amino-3-(4-isothiocyanatophenyl)propyl)cyclohexane-1,2-diamine-N,N′,N′,N″,N″-pentaacetic acid; DCPA, dipicolylamine alendronate; DFO, desferrioxamine; DO₃A, 1,4,7-tris(carboxymethyl)-1,4,7,10-tetraazacyclododecane; DOTA, 1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid; DTCBP₂, pentasodium mono(3-hydroxy-3,3-diphosphonato-propyl(methyl)dithiocarbamate; HMPAO, hexamethylpropyleneamine oxime; HYNIC, 6-hydrozinonicotinamide; NOTA, 1,4,7-triazacyclononane-N,N′,N″-triacetic acid; TETA, 1,4,8,11-tetraazacyclotetradecane-1,4,8, 11-tetraacetic acid.