Table 4.
Differences between the Cooling + Argon and Cooling group aEEG scores at the different time points.
| Time interval relative to HI | Difference in mean aEEG (Cooling + Argon–Cooling) | Standard error of the difference | Lower 95% C.I. for difference | Upper 95% C.I. for difference | p value |
|---|---|---|---|---|---|
| Baseline (before HI) | − 0.482 | 0.614 | − 1.701 | 0.736 | 0.434 |
| 0–6 h | 0.299 | 0.614 | − 0.920 | 1.517 | 0.628 |
| 7–12 h | 0.773 | 0.614 | − 0.446 | 1.991 | 0.211 |
| 13–18 h | 1.542 | 0.625 | 0.301 | 2.782 | 0.015 |
| 19–24 h | 1.502 | 0.718 | 0.076 | 2.927 | 0.039 |
| 25–30 h | 1.324 | 0.625 | 0.084 | 2.565 | 0.037 |
| 31–36 h | 1.244 | 0.662 | − 0.069 | 2.558 | 0.063 |
| 37–42 h | 1.833 | 0.713 | 0.419 | 3.248 | 0.012 |
The Argon + Cooling group showed evidence of faster recovery of electrical activity compared to Cooling from the time period 13–18 h after hypoxia–ischemia onwards (p < 0.04 for all intervals except for p = 0.06 for 31–36 h). HI: hypoxia–ischemia. Bold emphasis indicates statistical significance.