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. Author manuscript; available in PMC: 2016 Jul 1.
Published in final edited form as: J Invest Dermatol. 2016 Jan;136(1):161–172. doi: 10.1038/JID.2015.378

Figure 1. Comparison of epidermal thickness, PASI, differentially expressed genes (DEGs), and meta-analysis-derived psoriasis transcriptome between Asian small, Asian intermediate, and Western large psoriasis.

Figure 1

(a) Asian small psoriasis with limited epidermal thickness in comparison to Asian intermediate or Western large psoriasis. (b) Western large psoriasis with higher PASI in comparison to Asian small or intermediate psoriasis. (c) Area-proportional Venn diagram comparing DEGs. 27.7% of all DEGs were shared by the three comparison subtypes. (d) DEGs among meta-analysis-derived psoriasis transcriptome for Affymetrix Human Genome U133 Plus 2.0 Array (MAD3)(Suarez-Farinas et al., 2012). 66.9% of the meta-analysis-derived psoriasis transcriptome was differentially expressed in all subtypes (> 2 FCH and < 0.05 FDR, PASI: Psoriasis Area and Severity Index, FCH: fold change, FDR: false discovery rate)