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. Author manuscript; available in PMC: 2016 Jan 28.
Published in final edited form as: Exp Neurol. 2014 Mar 25;256:7–16. doi: 10.1016/j.expneurol.2014.03.008

Fig. 5. MK-886 attenuates deficits in hippocampal long-term potentiation after FPI.

Fig. 5

(A) LTP measured over time in hippocampal slices from sham rats (black symbols, n=8) and FPI- injured rats injected with vehicle (grey symbols, n=7) or MK-886 (red symbols, n=6) 30 min prior to injury. (B) LTP measured in hippocampal slices from sham rats (black symbols, n=8) and FPI-injured rats injected with vehicle (grey symbols, n=7) or MK-886 30 minutes after FPI (green symbols, n=7) and 60 minutes after FPI (blue symbols, n=6). (C) Average LTP response (mean +/− SEM control slope) in all the groups measured at 58-60 minutes after induction of LTP. *p<0.05, **p<0.01, different from FPI vehicle, not significantly different from sham, one way ANOVA followed by Tukey's HSD.