Table 1. Deformation and collapse of biological particles—CCMV, TrV, and AdV.
Accumulated are the Young’s moduli for Hertzian E H and bending E b deformations, the beam strength and the cooperativity parameter m. The first (second) entries correspond to the exact (approximate) methods of parameter estimation. The model predictions for F col are compared with the peak forces (in parenthesis) from the spectra (Figs 4 and 5). For TrV and AdV particles, the shell thickness was estimated as described in the S3 Text.
| System | EH, GPa | Eb, GPa | , nN | m | Fcol, nN |
|---|---|---|---|---|---|
| CCMV (2-fold symmetry; in silico) | 0.013/0.012 | 0.50/0.50 | 1.70/1.25 | 1.7/1.5 | 0.67/0.69 (0.68) |
| CCMV (quasi-2-fold symmetry; in silico) | 0.011/0.011 | 0.37/0.35 | 1.50/1.25 | 1.4/1.6 | 0.58/0.64 (0.68) |
| CCMV (quasi-3-fold symmetry; in silico) | 0.012/0.012 | 0.52/0.46 | 1.75/1.33 | 1.4/1.6 | 0.58/0.64 (0.68) |
| empty CCMV (average; in vitro) | 0.019/0.023 | 0.85/0.81 | 1.90/1.00 | 1.2/1.3 | 0.56/0.78 (0.71) |
| empty TrV (average; in vitro) | 0.030/0.036 | 0.94/0.81 | 1.90/1.1 | 1.1/1.2 | 0.70/1.02 (0.69) |
| full TrV (average; in vitro) | 0.140/0.140 | 0.95/0.84 | 8.10/5.5 | 1.1/1.0 | 2.91/3.78 (3.00) |
| full AdV (2-fold symmetry; in vitro) | 0.037/0.040 | 0.35/0.29 | 10.0/5.0 | 1.2/1.4 | 2.58/4.05 (3.80) |
| full AdV (3-fold symmetry; in vitro) | 0.018/0.019 | 0.20/0.18 | 11.0/5.0 | 1.3/1.7 | 3.04/4.15 (4.30) |
| full AdV (5-fold symmetry; in vitro) | 0.021/0.023 | 0.14/0.13 | 5.10/3.7 | 1.1/1.0 | 2.03/2.35 (1.90) |